MS-PEG4-THP

• CAT Number: I044727
• CAS Number: 145927-73-7
• Molecular Formula: C14H28O8S
• Molecular Weight: 356.43
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-(oxan-2-yloxy)ethoxy]ethoxy]ethoxy]ethyl methanesulfonate
• InChI: InChI=1S/C14H28O8S/c1-23(15,16)22-13-11-19-9-7-17-6-8-18-10-12-21-14-4-2-3-5-20-14/h14H,2-13H2,1H3
• InChIKey: IHVHEXYPQZJGKH-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)OCCOCCOCCOCCOC1CCCCO1

MS-PEG4-THP（Cat No.:I044727）is a heterobifunctional polyethylene glycol (PEG) linker featuring a mesyl (methanesulfonyl, MS) group on one end and a tetrahydropyranyl (THP) group on the other, connected by a PEG4 spacer. The PEG4 chain enhances solubility, flexibility, and biocompatibility, making it ideal for biomedical applications. The MS group is a good leaving group for nucleophilic substitution reactions, while the THP group serves as a protective group for hydroxyl functionalities, removable under mild acidic conditions. MS-PEG4-THP is useful in stepwise functionalization, drug delivery systems, and advanced material design requiring temporary protection and reactive control.