Ms-PEG4-MS

• CAT Number: R002330
• CAS Number: 55400-73-2
• Molecular Formula: C10H22O9S2
• Molecular Weight: 350.41
• Purity: ≥95%
• Synonyms: 2-[2-[2-(2-methylsulfonyloxyethoxy)ethoxy]ethoxy]ethyl methanesulfonate
• InChI: InChI=1S/C10H22O9S2/c1-20(11,12)18-9-7-16-5-3-15-4-6-17-8-10-19-21(2,13)14/h3-10H2,1-2H3
• InChIKey: GKMDADHKHXRPPF-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)OCCOCCOCCOCCOS(=O)(=O)C

MS-PEG4-MS(CAT: R002330) is a symmetric homobifunctional PEGylated crosslinker containing two methylsulfonyl (MS) reactive groups connected by a short tetraethylene glycol (PEG4) spacer. The PEG chain enhances solubility in aqueous and organic systems while providing flexibility and reduced steric hindrance during conjugation. The MS groups selectively react with nucleophilic residues, such as thiols or amines, enabling stable covalent linkage of biomolecules, small molecules, or surfaces. With a balanced hydrophilic spacer and reactive ends, MS-PEG4-MS is widely used in bioconjugation, surface modification, and linker chemistry for drug delivery, diagnostics, and material science research, offering versatility for controlled molecular design.