MRT-83 hydrochloride

• CAT Number: I008199
• CAS Number: 1359944-60-7
• Molecular Formula: C31H31ClN4O5
• Molecular Weight: 575.05
• Purity: ≥95%
• Synonyms: 3,4,5-trimethoxy-N-[N’-[4-methyl-3-[(4-phenylbenzoyl)amino]phenyl]carbamimidoyl]benzamide;hydrochloride
• IUPAC Name: 3,4,5-trimethoxy-N-[N'-[4-methyl-3-[(4-phenylbenzoyl)amino]phenyl]carbamimidoyl]benzamide;hydrochloride
• InChI: InChI=1S/C31H30N4O5.ClH/c1-19-10-15-24(33-31(32)35-30(37)23-16-26(38-2)28(40-4)27(17-23)39-3)18-25(19)34-29(36)22-13-11-21(12-14-22)20-8-6-5-7-9-20;/h5-18H,1-4H3,(H,34,36)(H3,32,33,35,37);1H
• InChIKey: ZOQUUTBPNBYISX-UHFFFAOYSA-N
• SMILES: CC1=C(C=C(C=C1)N=C(N)NC(=O)C2=CC(=C(C(=C2)OC)OC)OC)NC(=O)C3=CC=C(C=C3)C4=CC=CC=C4.Cl

MRT-83 hydrochloride（Cat No.:I008199）is a selective antagonist of the MCHR1 (melanin-concentrating hormone receptor 1), a G protein-coupled receptor involved in energy homeostasis, feeding behavior, and mood regulation. By blocking MCHR1 signaling, MRT-83 hydrochloride is used to investigate mechanisms underlying obesity, metabolic syndrome, and psychiatric conditions such as anxiety and depression. The hydrochloride salt form enhances solubility and formulation stability for in vivo and in vitro studies. MRT-83 hydrochloride is a valuable research tool for probing MCH pathway modulation.