For research use only. Not for therapeutic Use.
MRL-494 Hydrochloride（Cat No.:I044329）is a synthetic antimicrobial compound known for its ability to inhibit bacterial outer membrane biogenesis. It exhibits potent activity against Gram-negative bacteria, including Escherichia coli, by targeting and disrupting lipopolysaccharide (LPS) transport processes. MRL-494 is particularly valuable for studying bacterial membrane integrity and resistance mechanisms, as it interferes with essential protein-protein interactions in the Lpt (lipopolysaccharide transport) pathway. The hydrochloride salt enhances its solubility and stability for in vitro applications. This compound is a useful research tool in antibiotic development and membrane biology studies.
| CAS Number | 2699937-04-5 |
| Synonyms | 3-cyclopropyl-N-(diaminomethylidene)-3-[[4-(diaminomethylideneamino)-6-[[4-[[2-[5-(4-fluorophenyl)tetrazol-2-yl]acetyl]amino]cyclohexyl]amino]-1,3,5-triazin-2-yl]amino]propanamide;hydrochloride |
| Molecular Formula | C26H36ClFN16O2 |
| Purity | ≥95% |
| IUPAC Name | 3-cyclopropyl-N-(diaminomethylidene)-3-[[4-(diaminomethylideneamino)-6-[[4-[[2-[5-(4-fluorophenyl)tetrazol-2-yl]acetyl]amino]cyclohexyl]amino]-1,3,5-triazin-2-yl]amino]propanamide;hydrochloride |
| InChI | InChI=1S/C26H35FN16O2.ClH/c27-15-5-3-14(4-6-15)21-40-42-43(41-21)12-20(45)32-16-7-9-17(10-8-16)33-24-37-25(39-26(38-24)36-23(30)31)34-18(13-1-2-13)11-19(44)35-22(28)29;/h3-6,13,16-18H,1-2,7-12H2,(H,32,45)(H4,28,29,35,44)(H6,30,31,33,34,36,37,38,39);1H |
| InChIKey | OUQBLPVSJWIYJV-UHFFFAOYSA-N |
| SMILES | C1CC1C(CC(=O)N=C(N)N)NC2=NC(=NC(=N2)NC3CCC(CC3)NC(=O)CN4N=C(N=N4)C5=CC=C(C=C5)F)N=C(N)N.Cl |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
