For research use only. Not for therapeutic Use.
MRGPRX1 Agonist 1（Cat No.:I017741）is a selective small-molecule activator of the Mas-related G-protein coupled receptor X1 (MRGPRX1), a receptor implicated in sensory neuron signaling, itch perception, and neuro-immune communication. By stimulating MRGPRX1, this compound enables detailed study of receptor pharmacology, intracellular signaling pathways, and mechanisms underlying chronic itch and pain. It is a valuable tool for exploring the role of MRGPRX1 in inflammatory and neurological disorders, offering insight into novel therapeutic strategies targeting sensory hypersensitivity and pruritus. Its specificity supports precise receptor-focused investigations.
| CAS Number | 2377379-39-8 |
| Synonyms | N-[2-(1-aminoisoquinolin-6-yl)oxy-4-methylphenyl]-2-methoxybenzenesulfonamide |
| Molecular Formula | C23H21N3O4S |
| Purity | ≥95% |
| IUPAC Name | N-[2-(1-aminoisoquinolin-6-yl)oxy-4-methylphenyl]-2-methoxybenzenesulfonamide |
| InChI | InChI=1S/C23H21N3O4S/c1-15-7-10-19(26-31(27,28)22-6-4-3-5-20(22)29-2)21(13-15)30-17-8-9-18-16(14-17)11-12-25-23(18)24/h3-14,26H,1-2H3,(H2,24,25) |
| InChIKey | BWEJNHRMGZUMNU-UHFFFAOYSA-N |
| SMILES | CC1=CC(=C(C=C1)NS(=O)(=O)C2=CC=CC=C2OC)OC3=CC4=C(C=C3)C(=NC=C4)N |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
