MreB Perturbing Compound A22 hydrochloride

For research use only. Not for therapeutic Use.

  • CAT Number: R065111
  • CAS Number: 22816-60-0
  • Molecular Formula: C8H9Cl3N2S
  • Molecular Weight: 271.59
  • Purity: ≥95%
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MreB Perturbing Compound A22 hydrochloride(Cat No.:R065111)is a small-molecule inhibitor that targets MreB, a bacterial actin homolog essential for maintaining cell shape, polarity, and cell wall synthesis. By binding to MreB, A22 disrupts its polymerization and dynamics, leading to defects in cell morphology, growth inhibition, and eventual lysis. The hydrochloride salt form improves solubility and handling for laboratory applications. A22 is widely used in microbiology and antibiotic research to study cytoskeletal function in prokaryotes and to explore novel antibacterial strategies targeting cell shape–determining proteins.


CAS Number 22816-60-0
Synonyms

(3,4-dichlorophenyl)methyl carbamimidothioate;hydrochloride

Molecular Formula C8H9Cl3N2S
Purity ≥95%
IUPAC Name (3,4-dichlorophenyl)methyl carbamimidothioate;hydrochloride
InChI InChI=1S/C8H8Cl2N2S.ClH/c9-6-2-1-5(3-7(6)10)4-13-8(11)12;/h1-3H,4H2,(H3,11,12);1H
InChIKey VBJNMXMOMSWRDV-UHFFFAOYSA-N
SMILES C1=CC(=C(C=C1CSC(=N)N)Cl)Cl.Cl
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