MPC 6827 hydrochloride

  • CAT Number: I011144
  • CAS Number: 917369-31-4
  • Molecular Formula: C17H18ClN3O
  • Molecular Weight: 315.801
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MPC 6827 hydrochloride (CAT: I011144) is a potent inhibitor of microtubule formation. It has been shown to effectively inhibit the polymerization of tubulin in vitro and disrupt microtubule formation in various cancer cell lines. With an IC50 range of 1.5 to 3.4 nM, MPC 6827 hydrochloride demonstrates high potency in its microtubule inhibitory activity. In addition to its effects on microtubules, it also exhibits pro-apoptotic characteristics, contributing to its potential as an anti-cancer agent. Both in vitro and in vivo studies have demonstrated the inhibitory effects of MPC 6827 hydrochloride on tumor growth.

Catalog Number I011144
CAS Number 917369-31-4
Molecular Formula

C17H18ClN3O

Purity 95%
Target Microtubule/Tubulin
Solubility Soluble to 100 mM in water and to 100 mM in DMSO
Storage Desiccate at RT
IUPAC Name N-(4-methoxyphenyl)-N,2-dimethylquinazolin-4-amine;hydrochloride
InChI InChI=1S/C17H17N3O.ClH/c1-12-18-16-7-5-4-6-15(16)17(19-12)20(2)13-8-10-14(21-3)11-9-13;/h4-11H,1-3H3;1H
InChIKey VYUWDIKZJLOZJL-UHFFFAOYSA-N
SMILES CC1=NC2=CC=CC=C2C(=N1)N(C)C3=CC=C(C=C3)OC.Cl

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