Momordicoside A

• CAT Number: R040307
• CAS Number: 75801-95-5
• Molecular Formula: C42H72O15
• Molecular Weight: 817.01
• Purity: ≥95%
• Synonyms: (3R,4R,5S,6S)-2-methyl-6-[(3S,8R,9R,10S,13R,14S,17R)-4,4,9,13,14-pentamethyl-3-[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3,7,8,10,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-17-yl]heptane-2,3,4,5-tetrol
• InChI: InChI=1S/C42H72O15/c1-19(27(44)32(49)35(52)39(4,5)53)20-13-14-42(8)25-11-9-21-22(40(25,6)15-16-41(20,42)7)10-12-26(38(21,2)3)57-37-34(51)31(48)29(46)24(56-37)18-54-36-33(50)30(47)28(45)23(17-43)55-36/h9,19-20,22-37,43-53H,10-18H2,1-8H3/t19-,20+,22+,23+,24+,25+,26-,27-,28+,29+,30-,31-,32+,33+,34+,35+,36+,37-,40-,41+,42-/m0/s1
• InChIKey: WBYJYPOPDKQBQJ-WVMSUIAMSA-N
• SMILES: C[C@@H]([C@H]1CC[C@@]2([C@@]1(CC[C@@]3([C@H]2CC=C4[C@H]3CC[C@@H](C4(C)C)O[C@H]5[C@@H]([C@H]([C@@H]([C@H](O5)CO[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O)O)O)O)C)C)C)[C@@H]([C@H]([C@H](C(C)(C)O)O)O)O

Momordicoside A（Cat No.:R040307）is a cucurbitane-type triterpenoid saponin isolated from Momordica charantia (bitter melon), a plant widely used in traditional medicine. It exhibits multiple pharmacological properties, including antidiabetic, anticancer, anti-inflammatory, and antiviral effects. Momordicoside A modulates glucose metabolism, enhances insulin sensitivity, and suppresses tumor cell proliferation by regulating pathways such as AMPK and NF-κB. It has been studied for potential therapeutic roles in managing diabetes, obesity, and cancer. As a bioactive natural product, momordicoside A is an important compound for pharmacological research and natural product–based drug discovery.