For research use only. Not for therapeutic Use.
MNG-14a(CAT: I040528) is an amphiphilic detergent specifically designed for the isolation, stabilization, and characterization of membrane proteins. Its unique architecture combines hydrophilic and hydrophobic regions, enabling efficient solubilization of membrane-bound targets while preserving their native conformation and biological activity. MNG-14a is particularly effective in supporting structural studies such as cryo-EM and X-ray crystallography, as well as functional assays requiring protein integrity. It is widely used in membrane protein research, including GPCRs, transporters, and ion channels. This reagent offers enhanced protein stability and compatibility across a range of biochemical environments, making it an essential tool for high-resolution structural and functional studies.
| CAS Number | 1257853-50-1 |
| Synonyms | [(2R,3R,4S,5R,6R)-4,5-dibenzoyloxy-6-[2-decyl-2-[[(2R,3R,4S,5R,6R)-3,4-dibenzoyloxy-6-(benzoyloxymethyl)-5-[(2R,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-(benzoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]dodecoxy]-3-[(2R,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-(benzoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl benzoate |
| Molecular Formula | C145H144O36 |
| Purity | ≥95% |
| IUPAC Name | [(2R,3R,4S,5R,6R)-4,5-dibenzoyloxy-6-[2-decyl-2-[[(2R,3R,4S,5R,6R)-3,4-dibenzoyloxy-6-(benzoyloxymethyl)-5-[(2R,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-(benzoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]oxymethyl]dodecoxy]-3-[(2R,3R,4S,5R,6R)-3,4,5-tribenzoyloxy-6-(benzoyloxymethyl)oxan-2-yl]oxyoxan-2-yl]methyl benzoate |
| InChI | InChI=1S/C145H144O36/c1-3-5-7-9-11-13-15-59-89-145(90-60-16-14-12-10-8-6-4-2,95-164-141-123(176-137(156)107-81-51-27-52-82-107)121(174-135(154)105-77-47-25-48-78-105)117(113(166-141)93-162-129(148)99-65-35-19-36-66-99)180-143-125(178-139(158)109-85-55-29-56-86-109)119(172-133(152)103-73-43-23-44-74-103)115(170-131(150)101-69-39-21-40-70-101)111(168-143)91-160-127(146)97-61-31-17-32-62-97)96-165-142-124(177-138(157)108-83-53-28-54-84-108)122(175-136(155)106-79-49-26-50-80-106)118(114(167-142)94-163-130(149)100-67-37-20-38-68-100)181-144-126(179-140(159)110-87-57-30-58-88-110)120(173-134(153)104-75-45-24-46-76-104)116(171-132(151)102-71-41-22-42-72-102)112(169-144)92-161-128(147)98-63-33-18-34-64-98/h17-58,61-88,111-126,141-144H,3-16,59-60,89-96H2,1-2H3/t111-,112-,113-,114-,115-,116-,117-,118-,119+,120+,121+,122+,123-,124-,125-,126-,141-,142-,143-,144-/m1/s1 |
| InChIKey | LDLBVAGXCYUFID-MZFGGPEPSA-N |
| SMILES | CCCCCCCCCCC(CCCCCCCCCC)(COC1C(C(C(C(O1)COC(=O)C2=CC=CC=C2)OC3C(C(C(C(O3)COC(=O)C4=CC=CC=C4)OC(=O)C5=CC=CC=C5)OC(=O)C6=CC=CC=C6)OC(=O)C7=CC=CC=C7)OC(=O)C8=CC=CC=C8)OC(=O)C9=CC=CC=C9)COC1C(C(C(C(O1)COC(=O)C1=CC=CC=C1)OC1C(C(C(C(O1)COC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
