MNBA (4-methyl-3-nitro-benzoic acid)

• CAT Number: I008121
• Molecular Formula: C8H7NO4
• Molecular Weight: 181.15
• Purity: ≥95%
• Synonyms: MNBA; 4methyl3nitrobenzoic acid;4-methyl-3-nitro-benzoic acid
• Solubility: Soluble in DMSO, not in water
• Storage: 0 - 4 °C for short term, or -20 °C for long term
• SMILES: O=C(O)C1=CC=C(C)C([N+]([O-])=O)=C1

4-Methyl-3-nitrobenzoic acid (MNBA) (Cat No.: I008121) is an organic compound featuring a nitro and methyl substituent on a benzoic acid core. It is widely used as an intermediate in pharmaceutical and chemical synthesis, particularly in the production of active pharmaceutical ingredients (APIs) and agrochemicals. MNBA serves as a key building block in the development of various heterocyclic compounds and fine chemicals. Its functional groups provide versatility in organic reactions, making it valuable for drug discovery, material science, and industrial chemistry applications.

Reference

1: Chen P, Zhang X, Guo H, Ma N, Li M, Liu Z, Zhang N, Hao X. Effect of 4-methyl-3-nitrobenzoic acid on non‑small cell lung cancer cell migration. Mol Med Report. 2011 Sep-Oct;4(5):947-53. doi: 10.3892/mmr.2011.527. Epub 2011 Jul 1. PubMed PMID: 21725598.2: Guo H, Li M, Chen P, Blake DJ, Kong X, Hao X, Niu R, Zhang N. 4-Methyl-3-nitro-benzoic acid, a migration inhibitor, prevents breast cancer metastasis in SCID mice. Cancer Lett. 2011 Jun 1;305(1):69-75. doi: 10.1016/j.canlet.2011.02.028. Epub 2011 Mar 22. Erratum in: Cancer Lett. 2012 Nov 28;324(2):232. PubMed PMID: 21429660.