MMAF-OMe

  • CAT Number: I005184
  • CAS Number: 863971-12-4
  • Molecular Formula: C40H67N5O8
  • Molecular Weight: 745.99
  • Purity: ≥95%
Inquiry Now

MMAF-OMe (Monomethyl auristatin F – O-methyl ester)(CAT: I005184) is a synthetic derivative of monomethyl auristatin F (MMAF), a potent antimitotic agent. It works by inhibiting tubulin polymerization, leading to cell cycle arrest and apoptosis in rapidly dividing cells. MMAF-OMe is commonly used in the development of antibody-drug conjugates (ADCs), where it serves as the cytotoxic payload linked to monoclonal antibodies that specifically target cancer cells. The O-methyl ester modification improves the stability of the compound, making it more suitable for targeted drug delivery. MMAF-OMe is a crucial tool in cancer therapy research, offering highly selective cytotoxicity while sparing normal cells.


Catalog Number I005184
CAS Number 863971-12-4
Molecular Formula C40H67N5O8
Purity ≥95%
Target tubulin
Solubility DMSO
Storage -20°C

Request a Quote