For research use only. Not for therapeutic Use.
MM41（Cat No.:I043963）is a synthetic small-molecule compound designed to target G-quadruplex structures in DNA, particularly within the promoter regions of oncogenes such as c-MYC. By stabilizing these four-stranded DNA configurations, MM41 inhibits transcription of oncogenes, leading to reduced tumor cell proliferation and induction of apoptosis. It has shown promise in preclinical cancer models, including pancreatic and breast cancer, for its ability to selectively target cancer cells while sparing normal tissues. MM41 represents a novel therapeutic approach in anticancer drug development, focusing on gene regulation through structural DNA targeting.
| CAS Number | 1429028-96-5 |
| Synonyms | 14-hydroxy-3-[3-(4-methylpiperazin-1-yl)propylamino]-10-[3-(4-methylpiperazin-1-yl)propylimino]-6,13-bis(3-morpholin-4-ylpropyl)-6,13-diazatetracyclo[6.6.2.04,16.011,15]hexadeca-1(14),2,4(16),8,11(15)-pentaene-5,7,12-trione |
| Molecular Formula | C44H66N10O6 |
| Purity | ≥95% |
| IUPAC Name | 14-hydroxy-3-[3-(4-methylpiperazin-1-yl)propylamino]-10-[3-(4-methylpiperazin-1-yl)propylimino]-6,13-bis(3-morpholin-4-ylpropyl)-6,13-diazatetracyclo[6.6.2.04,16.011,15]hexadeca-1(14),2,4(16),8,11(15)-pentaene-5,7,12-trione |
| InChI | InChI=1S/C44H66N10O6/c1-47-15-19-49(20-16-47)9-3-7-45-35-31-33-38-37-34(42(56)53(43(57)39(35)37)13-5-11-51-23-27-59-28-24-51)32-36(46-8-4-10-50-21-17-48(2)18-22-50)40(38)44(58)54(41(33)55)14-6-12-52-25-29-60-30-26-52/h31-32,45,55H,3-30H2,1-2H3 |
| InChIKey | KOQWCTULEQQTBE-UHFFFAOYSA-N |
| SMILES | CN1CCN(CC1)CCCNC2=CC3=C(N(C(=O)C4=C3C5=C2C(=O)N(C(=O)C5=CC4=NCCCN6CCN(CC6)C)CCCN7CCOCC7)CCCN8CCOCC8)O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
