ML339

• CAT Number: I045836
• CAS Number: 2579689-83-9
• Molecular Formula: C26H32ClN3O5
• Molecular Weight: 502.00
• Purity: ≥95%
• Synonyms: N-[(1S,5R)-9-[2-(2-chloroanilino)-2-oxoethyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3,4,5-trimethoxybenzamide
• IUPAC Name: N-[(1R,5S)-9-[2-(2-chloroanilino)-2-oxoethyl]-9-azabicyclo[3.3.1]nonan-3-yl]-3,4,5-trimethoxybenzamide
• InChI: InChI=1S/C26H32ClN3O5/c1-33-22-11-16(12-23(34-2)25(22)35-3)26(32)28-17-13-18-7-6-8-19(14-17)30(18)15-24(31)29-21-10-5-4-9-20(21)27/h4-5,9-12,17-19H,6-8,13-15H2,1-3H3,(H,28,32)(H,29,31)/t17?,18-,19+
• InChIKey: SSPYAPRDKNCABY-YQQQUEKLSA-N
• SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)NC2C[C@H]3CCC[C@@H](C2)N3CC(=O)NC4=CC=CC=C4Cl

ML339（Cat No.:I045836）is a small-molecule inhibitor of the enzyme stearoyl-CoA desaturase-1 (SCD1), which catalyzes the formation of monounsaturated fatty acids from saturated fatty acyl-CoAs. By blocking SCD1 activity, ML339 disrupts lipid metabolism, leading to alterations in membrane composition, energy storage, and signaling pathways. This makes it a valuable tool for studying metabolic diseases, cancer, and obesity, where SCD1 is often dysregulated. ML339 has been applied in research on tumor growth, insulin resistance, and lipid homeostasis, supporting therapeutic exploration of SCD1 as a metabolic and oncological target.