ML 792 - CAS 1644342-14-2

ML-792 (CAT: I012899) is a novel and potent inhibitor of SUMO-activating enzyme (SAE), which is involved in the process of SUMOylation. By selectively blocking SAE enzyme activity, ML-792 effectively inhibits the overall SUMOylation process. SUMOylation is a post-translational modification that plays a crucial role in various cellular processes, including protein stability, subcellular localization, and protein-protein interactions. By decreasing total SUMOylation, ML-792 has shown promising anti-cancer properties, including the inhibition of cancer cell proliferation. The inhibition of SAE by ML-792 represents a potential therapeutic strategy for targeting SUMOylation pathways in cancer treatment.

Catalog Number: I012899

CAS Number: 1644342-14-2

Molecular Formula: C21H23BrN6O5S

Molecular Weight:551.42

Purity: ≥95%

* For research use only. Not for human or veterinary use.

Synonym

SynonymsML 792;((1R,2S,4R)-4-((5-(1-(3-bromobenzyl)-1H-pyrazole-3-carbonyl)pyrimidin-4-yl)amino)-2-hydroxycyclopentyl)methyl sulfamate

Property

Molecular Formula: C21H23BrN6O5S
Molecular Weight551.42
Target:SUMO-activating enzyme
Purity≥95%