ML-211（Cat No.:I044336）is a selective and potent small-molecule activator of NFE2L2 (Nrf2), a transcription factor that regulates cellular antioxidant and cytoprotective responses. By disrupting the Nrf2–Keap1 interaction, ML-211 promotes Nrf2 nuclear translocation and activation of downstream genes involved in detoxification, oxidative stress resistance, and inflammation control. It has shown potential in models of neurodegenerative diseases, cancer, and inflammatory disorders. ML-211 is widely used in research focused on redox biology, chemoprevention, and cellular defense mechanisms, supporting the development of therapeutics that harness the protective effects of Nrf2 signaling.