For research use only. Not for therapeutic Use.
MK-6240 precursor（Cat No.:I045779）is a synthetic intermediate used in the preparation of MK-6240, a highly selective PET imaging tracer for tau neurofibrillary tangles in Alzheimer’s disease and related tauopathies. The precursor contains a chemical handle suitable for radiolabeling, typically with fluorine-18, enabling the final compound’s use in positron emission tomography. Researchers utilize MK-6240 precursor in radiochemistry and neuroimaging studies to develop high-purity tracers for clinical and preclinical applications. Its stability and reactivity make it essential for producing MK-6240, supporting advances in neurodegenerative disease diagnostics and therapeutic monitoring.
| CAS Number | 1841444-11-8 |
| Synonyms | tert-butyl N-[(2-methylpropan-2-yl)oxycarbonyl]-N-(6-nitro-3-pyrrolo[2,3-c]pyridin-1-ylisoquinolin-5-yl)carbamate |
| Molecular Formula | C26H27N5O6 |
| Purity | ≥95% |
| IUPAC Name | tert-butyl N-[(2-methylpropan-2-yl)oxycarbonyl]-N-(6-nitro-3-pyrrolo[2,3-c]pyridin-1-ylisoquinolin-5-yl)carbamate |
| InChI | InChI=1S/C26H27N5O6/c1-25(2,3)36-23(32)30(24(33)37-26(4,5)6)22-18-13-21(28-14-17(18)7-8-19(22)31(34)35)29-12-10-16-9-11-27-15-20(16)29/h7-15H,1-6H3 |
| InChIKey | ABEKIBZOSUPLHC-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)N(C1=C(C=CC2=CN=C(C=C21)N3C=CC4=C3C=NC=C4)[N+](=O)[O-])C(=O)OC(C)(C)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
