Mitochondrial fusion promoter M1

• CAT Number: I045628
• CAS Number: 219315-22-7
• Molecular Formula: C14H10Cl4N2O
• Molecular Weight: 364.05
• Purity: ≥95%
• Synonyms: 4-chloro-2-[(E)-C-methyl-N-(2,4,6-trichloroanilino)carbonimidoyl]phenol
• InChI: InChI=1S/C14H10Cl4N2O/c1-7(10-4-8(15)2-3-13(10)21)19-20-14-11(17)5-9(16)6-12(14)18/h2-6,20-21H,1H3/b19-7+
• InChIKey: CYVDGZYJHHYIIU-FBCYGCLPSA-N
• SMILES: CC(=NNC1=C(C=C(C=C1Cl)Cl)Cl)C2=C(C=CC(=C2)Cl)O

Mitochondrial fusion promoter M1 (Cat No.: I045628) is a small-molecule research compound designed to enhance mitochondrial fusion, a process critical for maintaining mitochondrial health, bioenergetics, and cellular homeostasis. By promoting the merging of mitochondrial membranes, M1 supports mitochondrial network integrity, protects against fragmentation, and may improve cellular resilience under stress. This makes it a valuable tool for studying mitochondrial dynamics, neurodegeneration, metabolic disorders, and age-related diseases. Although not a therapeutic agent, M1 contributes to advancing research on mitochondrial quality control and potential therapeutic strategies.

Reference

[1]. Surinkaew P, et, al. Mitochondrial Fusion Promoter Alleviates Brain Damage in Rats with Cardiac Ischemia/Reperfusion Injury. J Alzheimers Dis. 2020;77(3):993-1003.
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[2]. Wang D, et, al. A small molecule promotes mitochondrial fusion in mammalian cells. Angew Chem Int Ed Engl. 2012 Sep 10;51(37):9302-5.
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[3]. Asalla S, et, al. Restoring Mitochondrial Function: A Small Molecule-mediated Approach to Enhance Glucose Stimulated Insulin Secretion in Cholesterol Accumulated Pancreatic beta cells. Sci Rep. 2016 Jun 10;6:27513.
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