Mito-TRFS

• CAT Number: I032367
• CAS Number: 1859102-62-7
• Molecular Formula: C38H34IN2O5PS2
• Molecular Weight: 820.70
• Purity: ≥95%
• Synonyms: 2-[2-[6-(dithiolan-4-yloxycarbonylamino)-1,3-dioxobenzo[de]isoquinolin-2-yl]ethoxy]ethyl-triphenylphosphanium;iodide
• InChI: InChI=1S/C38H33N2O5PS2.HI/c41-36-32-18-10-17-31-34(39-38(43)45-27-25-47-48-26-27)20-19-33(35(31)32)37(42)40(36)21-22-44-23-24-46(28-11-4-1-5-12-28,29-13-6-2-7-14-29)30-15-8-3-9-16-30;/h1-20,27H,21-26H2;1H
• InChIKey: UKWAKZCQJRRDFN-UHFFFAOYSA-N
• SMILES: C1C(CSS1)OC(=O)NC2=C3C=CC=C4C3=C(C=C2)C(=O)N(C4=O)CCOCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7.[I-]

Mito-TRFS（Cat No.:I032367）is a mitochondria-targeted fluorescent probe engineered for selective and sensitive detection of hydrogen sulfide (H₂S) within the mitochondrial matrix. Featuring a triphenylphosphonium (TPP) moiety for mitochondrial localization, Mito-TRFS reacts rapidly with H₂S to produce a strong fluorescence signal, enabling real-time visualization of mitochondrial H₂S dynamics. This probe is instrumental in exploring the role of H₂S in mitochondrial function, bioenergetics, redox regulation, and apoptosis. Mito-TRFS is widely used in studies of neurodegeneration, cardiovascular health, and metabolic disorders, offering deep insights into H₂S signaling in mitochondrial physiology and pathophysiology.