For research use only. Not for therapeutic Use.
Mito-apocynin (C11)(CAT: I016212) is a mitochondria-targeted derivative of apocynin, engineered by conjugation to a triphenylphosphonium (TPP⁺) cation through an 11-carbon alkyl chain. This design enables selective accumulation within mitochondria, where it functions as a potent inhibitor of NADPH oxidase–derived reactive oxygen species (ROS). By reducing mitochondrial oxidative stress, Mito-apocynin (C11) has been shown to protect against neurodegeneration, cardiovascular injury, and metabolic dysfunction. Its unique mechanism makes it a valuable research tool for studying redox biology, mitochondrial dysfunction, and inflammation-associated pathologies. Applications span neurological disease models, ischemia–reperfusion injury, and metabolic disease research requiring targeted ROS modulation.
| CAS Number | 1254044-38-6 |
| Synonyms | 11-(4-hydroxy-3-methoxybenzoyl)oxyundecyl-triphenylphosphanium;bromide |
| Molecular Formula | C37H44BrO4P |
| Purity | ≥95% |
| IUPAC Name | 11-(4-hydroxy-3-methoxybenzoyl)oxyundecyl-triphenylphosphanium;bromide |
| InChI | InChI=1S/C37H43O4P.BrH/c1-40-36-30-31(26-27-35(36)38)37(39)41-28-18-7-5-3-2-4-6-8-19-29-42(32-20-12-9-13-21-32,33-22-14-10-15-23-33)34-24-16-11-17-25-34;/h9-17,20-27,30H,2-8,18-19,28-29H2,1H3;1H |
| InChIKey | VWMXQDPFRLJGQR-UHFFFAOYSA-N |
| SMILES | COC1=C(C=CC(=C1)C(=O)OCCCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4)O.[Br-] |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
