Mirtazapine

• CAT Number: A000984
• CAS Number: 85650-52-8
• Molecular Formula: C17H19N3
• Molecular Weight: 265.4
• Purity: ≥95%
• Synonyms: Remeron; 85650-52-8; Mepirzepine; Remergil; Zispin
• Storage: -20°C
• IUPAC Name: 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene
• InChI: 1S/C17H19N3/c1-19-9-10-20-16(12-19)15-7-3-2-5-13(15)11-14-6-4-8-18-17(14)20/h2-8,16H,9-12H2,1H3
• InChIKey: RONZAEMNMFQXRA-UHFFFAOYSA-N
• SMILES: CN1CCN2C(C1)C3=CC=CC=C3CC4=C2N=CC=C4

Mirtazapine (CAS 85650-52-8) is an atypical antidepressant with noradrenergic and specific serotonergic activity. It works by blocking the α2 adrenergic auto- and heteroreceptors (enhancing serotonin release), and selectively antagonizing the 5-HT2 and 5-HT3 serotonin receptors in the central and peripheral nervous system. It also enhances serotonin neurotransmission at the 5-HT1 receptor and blocks the histaminergic (H1) and muscarinic receptors. Mirtazapine is not a serotonin or norepinephrine reuptake inhibitor.

Reference

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