For research use only. Not for therapeutic Use.
Minzasolmin（Cat No.:I045102）is an investigational orexin-2 receptor (OX2R) agonist being developed for the treatment of narcolepsy type 1 and other sleep-wake disorders. By selectively stimulating OX2R, Minzasolmin aims to restore wakefulness and stabilize sleep architecture in patients with orexin deficiency. It offers a novel, non-stimulant approach to managing excessive daytime sleepiness and cataplexy, distinguishing it from traditional stimulants and monoaminergic therapies. With favorable pharmacokinetics and central nervous system penetration, Minzasolmin is advancing through clinical development. Supplied for research in sleep neuroscience, orexin signaling, and neurotherapeutic innovation.
| CAS Number | 1802518-92-8 |
| Synonyms | N-[(2R)-1-(1H-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide |
| Molecular Formula | C23H31N5OS |
| Purity | ≥95% |
| IUPAC Name | N-[(2R)-1-(1H-indol-3-yl)hexan-2-yl]-2-(4-methylpiperazin-1-yl)-1,3-thiazole-5-carboxamide |
| InChI | InChI=1S/C23H31N5OS/c1-3-4-7-18(14-17-15-24-20-9-6-5-8-19(17)20)26-22(29)21-16-25-23(30-21)28-12-10-27(2)11-13-28/h5-6,8-9,15-16,18,24H,3-4,7,10-14H2,1-2H3,(H,26,29)/t18-/m1/s1 |
| InChIKey | GDFWCSZNQVAQGR-GOSISDBHSA-N |
| SMILES | CCCC[C@H](CC1=CNC2=CC=CC=C21)NC(=O)C3=CN=C(S3)N4CCN(CC4)C |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
