For research use only. Not for therapeutic Use.
mGluR2 antagonist 1（Cat No.:I015278）is a selective small-molecule inhibitor of metabotropic glutamate receptor 2 (mGluR2), a G-protein–coupled receptor involved in modulating glutamatergic neurotransmission. By blocking mGluR2 activity, it enhances synaptic glutamate signaling and alters neuronal excitability, making it a useful probe for studying central nervous system function. This antagonist is widely applied in research on psychiatric and neurological disorders, including depression, anxiety, and schizophrenia. Its receptor selectivity supports investigations into mGluR2-related signaling pathways, offering insights into potential therapeutic strategies for mood regulation and cognitive enhancement.
| CAS Number | 1432728-49-8 |
| Synonyms | 7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide |
| Molecular Formula | C21H16FN3O3 |
| Purity | ≥95% |
| IUPAC Name | 7-[(2,5-dioxopyrrolidin-1-yl)methyl]-4-(4-fluorophenyl)quinoline-2-carboxamide |
| InChI | InChI=1S/C21H16FN3O3/c22-14-4-2-13(3-5-14)16-10-18(21(23)28)24-17-9-12(1-6-15(16)17)11-25-19(26)7-8-20(25)27/h1-6,9-10H,7-8,11H2,(H2,23,28) |
| InChIKey | XSTBUOHORFUCIB-UHFFFAOYSA-N |
| SMILES | C1CC(=O)N(C1=O)CC2=CC3=C(C=C2)C(=CC(=N3)C(=O)N)C4=CC=C(C=C4)F |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
