MEVALONIC ACID, R, PYROPHOSPHATE

• CAT Number: M002147
• CAS Number: 103025-21-4
• Molecular Formula: C6H14O10P2
• Molecular Weight: 308.12
• Purity: ≥95%
• Synonyms: MEVALONIC ACID, R, PYROPHOSPHATE
• Storage: Desiccate at RT
• IUPAC Name: (3R)-3-hydroxy-5-[hydroxy(phosphonooxy)phosphoryl]oxy-3-methylpentanoic acid
• InChI: InChI=1S/C6H14O10P2/c1-6(9,4-5(7)8)2-3-15-18(13,14)16-17(10,11)12/h9H,2-4H2,1H3,(H,7,8)(H,13,14)(H2,10,11,12)/t6-/m1/s1
• InChIKey: SIGQQUBJQXSAMW-ZCFIWIBFSA-N
• SMILES: C[C@@](CCOP(=O)(O)OP(=O)(O)O)(CC(=O)O)O

(R)-Mevalonic acid pyrophosphate (Cat No.:M002147) is a key intermediate in the mevalonate pathway, essential for the biosynthesis of isoprenoids, cholesterol, and other terpenoids. With the molecular formula C6H14O10P2, it is the diphosphorylated form of (R)-mevalonic acid. This compound plays a central role in cellular metabolism, particularly in the synthesis of steroid hormones, dolichols, and ubiquinones. Produced enzymatically from mevalonate-5-phosphate, it is further converted to isopentenyl pyrophosphate (IPP). It is commonly studied in biochemistry, pharmacology, and metabolic engineering, especially regarding statin mechanisms and cholesterol-lowering drug research.