Methylsulfonylacetonitrile

• CAT Number: R070802
• CAS Number: 2274-42-2
• Molecular Formula: C3H5NO2S
• Molecular Weight: 119.14
• Purity: ≥95%
• Storage: RT
• IUPAC Name: 2-methylsulfonylacetonitrile
• InChI: InChI=1S/C3H5NO2S/c1-7(5,6)3-2-4/h3H2,1H3
• InChIKey: FOTRKCAZUSJCQD-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)CC#N

Methylsulfonylacetonitrile(CAT: R070802) is a highly functionalized organic compound featuring both a nitrile (–CN) group and a methylsulfonyl (–SO₂CH₃) moiety attached to a methylene carbon. This combination of electron-withdrawing groups enhances the compound’s acidity and reactivity, making it a useful intermediate in organic synthesis. It is particularly valuable in the preparation of heterocycles, pharmaceuticals, and agrochemicals, where it can undergo nucleophilic substitutions, condensations, or cyclizations. Methylsulfonylacetonitrile is commonly used in medicinal chemistry as a precursor to bioactive molecules, especially those requiring sulfone-linked structures. Its stability and synthetic versatility make it an important reagent in building complex, functionalized organic frameworks.