Methylamino-PEG4-acid

• CAT Number: I016234
• CAS Number: 1283658-71-8
• Molecular Formula: C12H25NO6
• Molecular Weight: 279.33
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-(methylamino)ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C12H25NO6/c1-13-3-5-17-7-9-19-11-10-18-8-6-16-4-2-12(14)15/h13H,2-11H2,1H3,(H,14,15)
• InChIKey: NVNPCETYZYDTLZ-UHFFFAOYSA-N
• SMILES: CNCCOCCOCCOCCOCCC(=O)O

Methylamino-PEG4-acid(CAT: I016234) is a heterobifunctional PEG-based linker featuring a terminal methylamino group and a carboxylic acid moiety, connected through a four-unit polyethylene glycol (PEG4) spacer. The methylamino group offers selective reactivity and enhanced polarity, while the terminal acid enables straightforward conjugation to amines via amide bond formation. The PEG4 spacer improves aqueous solubility, flexibility, and biocompatibility, while minimizing steric hindrance during coupling. This versatile reagent is widely applied in inhibitor synthesis, peptide–drug conjugates, and targeted delivery systems. Methylamino-PEG4-acid is particularly useful in cancer, immunology, and metabolic disease research where controlled linker chemistry is essential for drug discovery and bioconjugation.