Methyl Propiolate

• CAT Number: R025521
• CAS Number: 922-67-8
• Molecular Formula: C4H4O2
• Molecular Weight: 84.07
• Purity: ≥95%
• Synonyms: 2-Propynoic Acid Methyl Ester; Propiolic Acid Methyl Ester; (Carbomethoxy)acetylene; (Methoxycarbonyl)acetylene; Methyl 2-Propynoate; Methyl Acetylenecarboxylate; Methyl Acetylenemonocarboxylate; Methyl Ethynecarboxylate; Methyl Propargylate; Methyl
• Storage: -20°C
• IUPAC Name: methyl prop-2-ynoate
• InChI: InChI=1S/C4H4O2/c1-3-4(5)6-2/h1H,2H3
• InChIKey: IMAKHNTVDGLIRY-UHFFFAOYSA-N
• SMILES: COC(=O)C#C

Methyl propiolate (Cat No.: R025521) is a reactive alkyne ester with the molecular formula HC≡CCOOCH₃. It features both an electrophilic triple bond and an ester group, making it highly versatile in organic synthesis. Methyl propiolate readily undergoes nucleophilic addition, cycloaddition, and coupling reactions, and is commonly used in the preparation of heterocycles, natural products, and pharmaceuticals. Its electron-deficient triple bond allows selective functionalization, enabling the construction of complex molecular architectures. It is particularly valuable in click chemistry and polymer modification.