Methyl 3-Chloro-3-oxopropionate

• CAT Number: R029176
• CAS Number: 37517-81-0
• Molecular Formula: C4H5ClO3
• Molecular Weight: 136.53
• Purity: ≥95%
• Synonyms: (Carbomethoxy)acetyl chloride; (Methoxycarbonyl)acetyl chloride; 2-Methoxycarbonylacetyl chloride; 3-Chloro-3-oxopropanoic acid methyl ester; 3-Methoxy-3-oxopropanoyl chloride; Chlorocarbonylacetic acid methyl ester; Malonic acid chloride monomethyl
• Storage: -20°C
• IUPAC Name: methyl 3-chloro-3-oxopropanoate
• InChI: InChI=1S/C4H5ClO3/c1-8-4(7)2-3(5)6/h2H2,1H3
• InChIKey: UTBCRHAMJFMIIR-UHFFFAOYSA-N
• SMILES: COC(=O)CC(=O)Cl

Methyl 3-chloro-3-oxopropionate (Cat NO.: R029176) is a reactive organic intermediate containing ester, ketone, and chloro functional groups. Its structure makes it highly versatile for use in organic synthesis, particularly in the formation of heterocycles, pharmaceuticals, and agrochemicals. The electron-withdrawing chloro and carbonyl groups enhance its reactivity in nucleophilic substitution and condensation reactions. It is often used in the preparation of β-keto esters, enolates, and as a building block in the synthesis of complex molecules requiring functional group diversity and selective transformations.