Melanocyte-stimulating hormone release inhibiting factor

• CAT Number: P000135
• CAS Number: 2002-44-0
• Molecular Formula: C13H24N4O3
• Molecular Weight: 284.36
• Purity: ≥95%
• Synonyms: Alternative Names: Pro-Leu-Gly amide, MIF-I, PLG
• Target: Neuronal Signaling
• Storage: Desiccate at -20C
• IUPAC Name: (2S)-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-4-methyl-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
• InChI: InChI=1S/C13H24N4O3/c1-8(2)6-10(12(19)16-7-11(14)18)17-13(20)9-4-3-5-15-9/h8-10,15H,3-7H2,1-2H3,(H2,14,18)(H,16,19)(H,17,20)/t9-,10-/m0/s1
• InChIKey: NOOJLZTTWSNHOX-UWVGGRQHSA-N
• SMILES: CC(C)C[C@@H](C(=O)NCC(=O)N)NC(=O)[C@@H]1CCCN1

Melanocyte-Stimulating Hormone Release Inhibiting Factor (Cat No.:P000135) is a neuropeptide that modulates the release of melanocyte-stimulating hormone (MSH) from the pituitary gland. Also known as prolactin release-inhibiting factor, MIF plays a key role in neuroendocrine regulation by influencing melanogenesis, stress responses, and immune signaling. It acts within the hypothalamic-pituitary axis and may have overlapping functions with dopamine-mediated pathways. MIF is studied for its physiological relevance in skin pigmentation, inflammation, and hormonal balance, and is of interest in dermatological, neuroendocrine, and immunological research models.