MDL-43291

• CAT Number: I031805
• CAS Number: 129357-91-1
• Molecular Formula: C25H42O4S
• Molecular Weight: 438.67
• Purity: 98%
• Synonyms: MDL43291; MDL 43291; MDL-43291
• Solubility: To be determined
• Appearance: Solid powder
• Storage: Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
• IUPAC Name: 2-[[(2Z,4aS,8S,8aS)-2-(2-oxotetradecan-7-ylidene)-3,4,4a,5,6,7,8,8a-octahydrochromen-8-yl]sulfanyl]acetic acid
• InChI: InChI=1S/C25H42O4S/c1-3-4-5-6-7-12-20(13-9-8-11-19(2)26)22-17-16-21-14-10-15-23(25(21)29-22)30-18-24(27)28/h21,23,25H,3-18H2,1-2H3,(H,27,28)/b22-20-/t21-,23-,25-/m0/s1
• InChIKey: SOLABHDTQQWQEM-XXPBHPIPSA-N
• SMILES: CCCCCCC/C(=C/1\CC[C@@H]2CCC[C@@H]([C@H]2O1)SCC(=O)O)/CCCCC(=O)C

MDL-43291（Cat No.:I031805）is a selective inhibitor of the enzyme phosphodiesterase 3 (PDE3), which plays a critical role in regulating cellular cyclic AMP (cAMP) levels. By inhibiting PDE3, MDL-43291 increases cAMP accumulation, which can enhance various physiological responses such as vasodilation, heart contractility, and neurotransmitter release. This compound has potential therapeutic applications in conditions like heart failure and certain types of vascular diseases, where PDE3 inhibition could improve cardiac function and blood flow. However, its safety and efficacy require further investigation through clinical studies to fully understand its therapeutic potential.