• CAT Number: I007926
  • CAS Number: 1225208-44-5
  • Molecular Formula: C29H33ClN2O5
  • Molecular Weight: 525.04
  • Purity: ≥95%
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MDK08445(CAT: I007926) is an important intermediate for the synthesis of Cefiderocol, a potent antibiotic effective against a range of Gram-negative bacteria, including MDR strains. The catechol moiety on its 3-position side chain is an important feature that contributes to its high potency.

Catalog Number I007926
CAS Number 1225208-44-5

MDK08445; MDK 08445; MDK-08445. Cefiderocol-intermediate, Cefiderocol-precursor.;2-chloro-3,4-bis((4-methoxybenzyl)oxy)-N-(2-(pyrrolidin-1-yl)ethyl)benzamide

Molecular Formula


Purity 95%
Solubility Soluble in DMSO
Storage 0 - 4 °C for short term, or -20 °C for long term
InChI InChI=1S/C29H33ClN2O5/c1-34-23-9-5-21(6-10-23)19-36-26-14-13-25(29(33)31-15-18-32-16-3-4-17-32)27(30)28(26)37-20-22-7-11-24(35-2)12-8-22/h5-14H,3-4,15-20H2,1-2H3,(H,31,33)

</br>1. Preparation of intermediate of cephalosporin derivatives. Fukuda, Mayu; Watanabe, Takeaki; Kurita, Takanori; Yokota, Yutaka; Takeo, Masatoshi; Noguchi, Kouichi. PCT Int. Appl. (2016), WO 2016035847 A1 20160310, Language: Japanese, Database: CAPLUS </br>2.Pharmaceutical preparation comprising cephalosporin having catechol groups with improved stability, and manufacture thereof. Kawasaki, Hidenori; Kojima, Natsuko; Fujihira, Atsushi; Takahashi, Kanako; Matsubara, Fumihiko; Matsuoka, Nao. PCT Int. Appl. (2016), WO 2016035846 A1 20160310

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