Maprotiline Hydrochloride

• CAT Number: A000741
• CAS Number: 10347-81-6
• Molecular Formula: C20H24ClN
• Molecular Weight: 313.86
• Purity: ≥95%
• Synonyms: 10347-81-6; Maprotiline Hcl; Ludiomil; Psymion; Maprotilline HCl
• Target: Autophagy
• Solubility: Soluble in DMSO > 10 mM
• Storage: -20°C
• IUPAC Name: N-methyl-3-(1-tetracyclo[6.6.2.02,7.09,14]hexadeca-2,4,6,9,11,13-hexaenyl)propan-1-amine;hydrochloride
• InChI: 1S/C20H23N.ClH/c1-21-14-6-12-20-13-11-15(16-7-2-4-9-18(16)20)17-8-3-5-10-19(17)20;/h2-5,7-10,15,21H,6,11-14H2,1H3;1H
• InChIKey: NZDMFGKECODQRY-UHFFFAOYSA-N
• SMILES: CNCCCC12CCC(C3=CC=CC=C31)C4=CC=CC=C24.Cl

Maprotiline Hydrochloride (Cat No.: A000741) is the hydrochloride salt form of maprotiline, a tetracyclic antidepressant closely related to the tricyclic antidepressants with adrenergic activity and sedative properties. Maprotiline hydrochloride exerts its effect by blocking the re-uptake of norepinephrine, thereby increasing the synaptic concentration of norepinephrine in the central nervous system and subsequently prolonging the action of norepinephrine on central receptors.