Maoecrystal A

• CAT Number: I017091
• CAS Number: 96850-30-5
• Molecular Formula: C22H28O6
• Molecular Weight: 388.45
• Purity: ≥95%
• Synonyms: [(1S,2S,5R,7R,8S,10S,11R,13R)-10-hydroxy-12,12-dimethyl-6-methylidene-9,16-dioxo-14-oxapentacyclo[11.2.2.15,8.01,11.02,8]octadecan-7-yl] acetate
• InChI: InChI=1S/C22H28O6/c1-10-12-5-6-13-21(8-12,19(10)28-11(2)23)18(26)16(25)17-20(3,4)15-7-14(24)22(13,17)9-27-15/h12-13,15-17,19,25H,1,5-9H2,2-4H3/t12-,13-,15-,16+,17-,19-,21-,22-/m1/s1
• InChIKey: DCULYKVTBAXAER-XETVFITMSA-N
• SMILES: CC(=O)OC1C(=C)C2CCC3C1(C2)C(=O)C(C4C35COC(C4(C)C)CC5=O)O

Maoecrystal A(CAT: I017091) is a highly complex ent-kaurane diterpenoid first isolated from Isodon eriocalyx, a plant used in traditional Chinese medicine. It has drawn significant attention due to its potent anticancer properties, particularly its ability to inhibit the growth of drug-resistant cancer cells. Research indicates that Maoecrystal A induces apoptosis, disrupts tumor cell proliferation, and modulates signaling pathways involved in cancer progression. Its intricate polycyclic structure has also made it an important subject in synthetic organic chemistry, with numerous studies focused on total synthesis and structure–activity relationships. With dual value in oncology research and synthetic methodology development, Maoecrystal A stands as a remarkable natural product for advancing both drug discovery and chemical innovation.