Manidipine dihydrochloride

  • CAT Number: I005342
  • CAS Number: 89226-75-5
  • Molecular Formula: C35H40Cl2N4O6
  • Molecular Weight: 683.62
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Manidipine dihydrochloride (CAT: I005342), also known as Manidipine 2HCl or CV-4093, is a dihydropyridine compound that serves as a potent calcium channel blocker. Its pharmacological action involves inhibiting Ca2+ currents with an impressive IC50 value of 2.6 nM. By blocking calcium channels, Manidipine dihydrochloride reduces the influx of calcium ions into cells, leading to vasodilation and a decrease in blood pressure. This compound’s role as a calcium channel blocker highlights its significance in cardiovascular medicine, where it offers potential therapeutic applications in the management of hypertension and other cardiovascular conditions.

Catalog Number I005342
CAS Number 89226-75-5
Molecular Formula


Purity 95%
Target Calcium Channel
Solubility DMSO 20 mg/mL
Storage 3 years -20C powder
IC50 2.6 nM

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