Maleimide-C10-NHS ester

• CAT Number: I015103
• CAS Number: 87981-04-2
• Molecular Formula: C19H26N2O6
• Molecular Weight: 378.42
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 11-(2,5-dioxopyrrol-1-yl)undecanoate
• InChI: InChI=1S/C19H26N2O6/c22-15-10-11-16(23)20(15)14-8-6-4-2-1-3-5-7-9-19(26)27-21-17(24)12-13-18(21)25/h10-11H,1-9,12-14H2
• InChIKey: SGNVTRHWJGTNKV-UHFFFAOYSA-N
• SMILES: C1CC(=O)N(C1=O)OC(=O)CCCCCCCCCCN2C(=O)C=CC2=O

Maleimide-C10-NHS ester（Cat No.:I015103）is a heterobifunctional crosslinker designed for bioconjugation applications. Featuring a maleimide group and an N-hydroxysuccinimide (NHS) ester connected by a decyl (C10) spacer, it enables efficient coupling between sulfhydryl-containing molecules (via maleimide) and primary amines (via NHS ester). This dual reactivity makes it an essential tool for preparing antibody–drug conjugates, peptide labeling, protein modification, and surface functionalization. The long C10 spacer enhances flexibility and reduces steric hindrance, improving conjugation efficiency. Researchers use it in chemical biology, drug delivery, and biomaterials development.