Mal-PEG5-acid

• CAT Number: I017120
• CAS Number: 1286755-26-7
• Molecular Formula: C17H27NO9
• Molecular Weight: 389.40
• Purity: ≥95%
• Synonyms: 3-[2-[2-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoic acid
• InChI: InChI=1S/C17H27NO9/c19-15-1-2-16(20)18(15)4-6-24-8-10-26-12-14-27-13-11-25-9-7-23-5-3-17(21)22/h1-2H,3-14H2,(H,21,22)
• InChIKey: HFYDLVZXYONWDG-UHFFFAOYSA-N
• SMILES: C1=CC(=O)N(C1=O)CCOCCOCCOCCOCCOCCC(=O)O

Mal-PEG5-acid(CAT:I017120) is a heterobifunctional polyethylene glycol (PEG) linker featuring a maleimide group on one end and a carboxylic acid group on the other, connected by a five-unit PEG spacer. The maleimide moiety enables highly selective conjugation with sulfhydryl (–SH) groups, while the terminal carboxyl can be activated for coupling to amines, allowing versatile bioconjugation strategies. The PEG5 spacer imparts hydrophilicity, flexibility, and reduced steric hindrance, ensuring efficient reaction kinetics and improved solubility. Mal-PEG5-acid is widely used in protein labeling, antibody–drug conjugates (ADCs), surface modification, and drug delivery research, providing controlled spacing and stability in aqueous systems.