For research use only. Not for therapeutic Use.
Mal-PEG3-Boc(CAT: I016233) is a heterobifunctional PEG-based linker bearing a maleimide moiety and a Boc-protected amine, separated by a triethylene glycol (PEG3) spacer. The maleimide group reacts selectively with thiols, enabling site-specific conjugation to cysteine residues in peptides, proteins, or antibodies. The Boc-protected amine serves as a latent handle, which upon deprotection yields a primary amine for further functionalization or coupling. The PEG3 spacer enhances solubility, reduces steric interference, and improves biocompatibility. Mal-PEG3-Boc is highly useful in designing inhibitors, drug–protein conjugates, and bioconjugation strategies in cancer, metabolic, and immunological disease research where precision and stability are essential.
| CAS Number | 518044-35-4 |
| Synonyms | tert-butyl 3-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]propanoate |
| Molecular Formula | C17H27NO7 |
| Purity | ≥95% |
| IUPAC Name | tert-butyl 3-[2-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]ethoxy]propanoate |
| InChI | InChI=1S/C17H27NO7/c1-17(2,3)25-16(21)6-8-22-10-12-24-13-11-23-9-7-18-14(19)4-5-15(18)20/h4-5H,6-13H2,1-3H3 |
| InChIKey | GBAIKTRBCFEELB-UHFFFAOYSA-N |
| SMILES | CC(C)(C)OC(=O)CCOCCOCCOCCN1C(=O)C=CC1=O |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
