Mal-PEG1-Boc

• CAT Number: I016306
• CAS Number: 810677-16-8
• Molecular Formula: C13H19NO5
• Molecular Weight: 269.29
• Purity: ≥95%
• Synonyms: tert-butyl 3-[2-(2,5-dioxopyrrol-1-yl)ethoxy]propanoate
• InChI: InChI=1S/C13H19NO5/c1-13(2,3)19-12(17)6-8-18-9-7-14-10(15)4-5-11(14)16/h4-5H,6-9H2,1-3H3
• InChIKey: YFNQRZMVQPRONS-UHFFFAOYSA-N
• SMILES: CC(C)(C)OC(=O)CCOCCN1C(=O)C=CC1=O

Mal-PEG1-Boc(CAT: I016306) is a compact heterobifunctional polyethylene glycol (PEG) linker bearing a maleimide group on one end and a Boc-protected amine on the other, connected by a single ethylene glycol unit. The maleimide moiety enables site-specific conjugation to thiol-containing biomolecules, forming stable thioether linkages with cysteine residues in peptides, proteins, or other compounds. The Boc-protected amine serves as a protected functional handle that can be deprotected under acidic conditions to generate a free primary amine for subsequent coupling reactions. With its short PEG spacer, Mal-PEG1-Boc is ideal for applications requiring minimal distance between conjugated groups, including bioconjugation, probe design, and polymer modification.