For research use only. Not for therapeutic Use.
Mal-C2-cyclohexylcarboxyl-hydrazide hydrochloride (Cat No.: I045312) is a bifunctional linker molecule featuring a maleimide group for thiol-reactive conjugation and a hydrazide moiety for coupling with aldehydes or ketones. The C2 spacer provides flexibility, while the cyclohexylcarboxyl group enhances hydrophobic interactions and structural rigidity. This compound is widely used in bioconjugation, particularly for linking proteins, peptides, or small molecules in drug delivery systems and diagnostic applications. Its hydrochloride salt form improves stability and solubility, making it suitable for aqueous-phase biochemical and pharmaceutical research.
| CAS Number | 174422-72-1 |
| Synonyms | 4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carbohydrazide;hydrochloride |
| Molecular Formula | C12H18ClN3O3 |
| Purity | ≥95% |
| InChI | InChI=1S/C12H17N3O3.ClH/c13-14-12(18)9-3-1-8(2-4-9)7-15-10(16)5-6-11(15)17;/h5-6,8-9H,1-4,7,13H2,(H,14,18);1H |
| InChIKey | CKGAFBJFAXITJV-UHFFFAOYSA-N |
| SMILES | C1CC(CCC1CN2C(=O)C=CC2=O)C(=O)NN.Cl |
| Reference | [1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
