For research use only. Not for therapeutic Use.
MAGL-IN-5（Cat No.:I005702）is a potent and selective inhibitor of monoacylglycerol lipase (MAGL), an enzyme responsible for hydrolyzing 2-arachidonoylglycerol (2-AG), a key endocannabinoid. By blocking MAGL activity, MAGL-IN-5 increases 2-AG levels, enhancing cannabinoid receptor signaling and exerting analgesic, anti-inflammatory, and neuroprotective effects. It is widely used in studies of endocannabinoid system modulation, pain management, neurodegeneration, and inflammation. With strong selectivity over FAAH and other serine hydrolases, MAGL-IN-5 is a valuable pharmacological tool for dissecting MAGL’s role in physiological and pathological processes.
| CAS Number | 359714-55-9 |
| Synonyms | benzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate |
| Molecular Formula | C18H17N3O5 |
| Purity | ≥95% |
| IUPAC Name | benzyl N-[4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3-yl)-2-methylphenyl]carbamate |
| InChI | InChI=1S/C18H17N3O5/c1-12-10-14(21-18(23)26-17(20-21)24-2)8-9-15(12)19-16(22)25-11-13-6-4-3-5-7-13/h3-10H,11H2,1-2H3,(H,19,22) |
| InChIKey | QTENHWTVRQKWRI-UHFFFAOYSA-N |
| SMILES | CC1=C(C=CC(=C1)N2C(=O)OC(=N2)OC)NC(=O)OCC3=CC=CC=C3 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
