m-PEG6-thiol

• CAT Number: I016495
• CAS Number: 441771-60-4
• Molecular Formula: C13H28O6S
• Molecular Weight: 312.42
• Purity: ≥95%
• Synonyms: 2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethanethiol
• InChI: InChI=1S/C13H28O6S/c1-14-2-3-15-4-5-16-6-7-17-8-9-18-10-11-19-12-13-20/h20H,2-13H2,1H3
• InChIKey: FCNSUDTWFXNQBG-UHFFFAOYSA-N
• SMILES: COCCOCCOCCOCCOCCOCCS

m-PEG6-thiol(CAT: I016495) is a monofunctional polyethylene glycol derivative containing a six-unit PEG spacer terminated with a free thiol group. The PEG6 chain enhances solubility and flexibility, reducing steric hindrance and nonspecific interactions. The thiol functionality enables selective conjugation to maleimide, gold, or other thiol-reactive surfaces, making it highly valuable for bioconjugation, surface coating, and nanoparticle stabilization. With its hydrophilic backbone, m-PEG6-thiol improves stability, dispersibility, and biocompatibility of modified molecules and materials. This reagent is commonly applied in drug delivery systems, biomaterials, and diagnostics where controlled surface functionalization and reduced protein adsorption are critical.