m-PEG6-amino-Mal

• CAT Number: I016385
• CAS Number: 1644231-07-1
• Molecular Formula: C20H34N2O9
• Molecular Weight: 446.49
• Purity: ≥95%
• Synonyms: 3-(2,5-dioxopyrrol-1-yl)-N-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethyl]propanamide
• InChI: InChI=1S/C20H34N2O9/c1-26-8-9-28-12-13-30-16-17-31-15-14-29-11-10-27-7-5-21-18(23)4-6-22-19(24)2-3-20(22)25/h2-3H,4-17H2,1H3,(H,21,23)
• InChIKey: BPYWOIZSFVKCGV-UHFFFAOYSA-N
• SMILES: COCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O

m-PEG6-amino-Mal(CAT: I016385) is a heterobifunctional polyethylene glycol (PEG) linker featuring a terminal amine group and a maleimide moiety connected via a PEG6 spacer. The primary amine provides a reactive site for coupling to activated esters (such as NHS or PFP esters) or carboxyl groups, while the maleimide selectively reacts with thiol-containing molecules (e.g., cysteine residues in peptides, proteins, or antibodies) to form stable thioether bonds. The PEG6 spacer improves solubility, reduces steric hindrance, and enhances molecular flexibility, enabling efficient conjugation. This reagent is valuable in bioconjugation, antibody-drug conjugates, protein labeling, and biomedical research requiring site-specific and stable linkage strategies.