m-PEG3-SH

• CAT Number: I016299
• CAS Number: 31521-83-2
• Molecular Formula: C7H16O3S
• Molecular Weight: 180.27
• Purity: ≥95%
• Synonyms: 2-[2-(2-methoxyethoxy)ethoxy]ethanethiol
• InChI: InChI=1S/C7H16O3S/c1-8-2-3-9-4-5-10-6-7-11/h11H,2-7H2,1H3
• InChIKey: DMFFSDWRRLCKKN-UHFFFAOYSA-N
• SMILES: COCCOCCOCCS

m-PEG3-SH(CAT: I016299) is a monofunctional polyethylene glycol (PEG) derivative featuring a methoxy group on one terminus and a thiol group on the other. The PEG3 spacer, consisting of three ethylene glycol units, offers short but flexible hydrophilic spacing that improves solubility and reduces steric hindrance in conjugation reactions. The thiol group provides a reactive handle for selective coupling with maleimide, haloacetyl, or gold-surface groups, forming stable thioether or thiolate linkages. The methoxy-capped end enhances stability and prevents undesired side reactions. m-PEG3-SH is commonly used in bioconjugation, nanomaterial surface modification, and drug delivery applications requiring short thiol-terminated PEG linkers.