m-PEG12-NHS ester

• CAT Number: I016647
• CAS Number: 2207596-93-6
• Molecular Formula: C30H55NO16
• Molecular Weight: 685.75
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
• InChI: InChI=1S/C30H55NO16/c1-35-6-7-37-10-11-39-14-15-41-18-19-43-22-23-45-26-27-46-25-24-44-21-20-42-17-16-40-13-12-38-9-8-36-5-4-30(34)47-31-28(32)2-3-29(31)33/h2-27H2,1H3
• InChIKey: ZMXRHHJWXLKMTL-UHFFFAOYSA-N
• SMILES: COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O

m-PEG12-NHS ester(CAT: I016647) is a monofunctional polyethylene glycol (PEG) derivative featuring a 12-unit PEG spacer with a terminal N-hydroxysuccinimide (NHS) ester. The activated NHS group reacts efficiently with primary amines under mild conditions to form stable amide bonds, enabling reliable conjugation to proteins, peptides, antibodies, or small molecules. The PEG12 spacer imparts excellent water solubility, flexibility, and reduced steric hindrance, improving biocompatibility and stability of conjugates. m-PEG12-NHS ester is widely used in bioconjugation, drug delivery, PEGylation, surface modification, and nanotechnology, where controlled linker length and hydrophilicity are essential for enhancing pharmacokinetics, reducing aggregation, and improving molecular interactions.