m-C-tri(CH2-PEG1-NHS ester)

• CAT Number: I016435
• CAS Number: 173414-89-6
• Molecular Formula: C26H33N3O15
• Molecular Weight: 627.55
• Purity: ≥95%
• Synonyms: (2,5-dioxopyrrolidin-1-yl) 3-[3-[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]-2-[[3-(2,5-dioxopyrrolidin-1-yl)oxy-3-oxopropoxy]methyl]-2-methylpropoxy]propanoate
• InChI: InChI=1S/C26H33N3O15/c1-26(14-39-11-8-23(36)42-27-17(30)2-3-18(27)31,15-40-12-9-24(37)43-28-19(32)4-5-20(28)33)16-41-13-10-25(38)44-29-21(34)6-7-22(29)35/h2-16H2,1H3
• InChIKey: IMRQCGBFYSSHHS-UHFFFAOYSA-N
• SMILES: CC(COCCC(=O)ON1C(=O)CCC1=O)(COCCC(=O)ON2C(=O)CCC2=O)COCCC(=O)ON3C(=O)CCC3=O

m-C-tri(CH₂-PEG1-NHS ester)(CAT: I016435) is a multifunctional trifunctional PEG-based crosslinker featuring three NHS ester groups anchored on a central meta-substituted benzene scaffold. Each NHS ester reacts efficiently with primary amines on proteins, peptides, or other biomolecules, forming stable amide linkages. The short PEG1 spacers enhance solubility while minimizing steric hindrance, allowing efficient, site-specific conjugation in aqueous systems. This trifunctional design enables simultaneous modification of multiple biomolecules or surfaces, making it a versatile reagent for protein crosslinking, nanoparticle functionalization, and biomaterial engineering. Its compact architecture provides precise control in bioconjugation applications where multivalency and stability are essential.