LyP-1 TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I044267
  • Molecular Formula: C38H66F3N17O14S2
  • Molecular Weight: 1106.16
  • Purity: ≥95%
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LyP-1 TFA(Cat No.:I044267)is a tumor-homing peptide with the sequence CGNKRTRGC, commonly used in cancer research for targeted delivery of therapeutic agents. It specifically binds to tumor lymphatics and certain tumor cell receptors, facilitating selective accumulation in malignant tissues. The peptide enhances cellular uptake and penetration, making it a promising tool for imaging, drug delivery, and anti-cancer therapy. The TFA (trifluoroacetate) form refers to the peptide being purified and stored as a trifluoroacetate salt, a common counterion used to stabilize peptides during synthesis and formulation.


Synonyms

(4R,10S,13S,16S,19S,22S,28R)-28-amino-19-(4-aminobutyl)-22-(2-amino-2-oxoethyl)-10,16-bis[3-(diaminomethylideneamino)propyl]-13-[(1R)-1-hydroxyethyl]-6,9,12,15,18,21,24,27-octaoxo-1,2-dithia-5,8,11,14,17,20,23,26-octazacyclononacosane-4-carboxylic acid;2,2,2-trifluoroacetic acid

Molecular Formula C38H66F3N17O14S2
Purity ≥95%
IUPAC Name (4R,10S,13S,16S,19S,22S,28R)-28-amino-19-(4-aminobutyl)-22-(2-amino-2-oxoethyl)-10,16-bis[3-(diaminomethylideneamino)propyl]-13-[(1R)-1-hydroxyethyl]-6,9,12,15,18,21,24,27-octaoxo-1,2-dithia-5,8,11,14,17,20,23,26-octazacyclononacosane-4-carboxylic acid;2,2,2-trifluoroacetic acid
InChI InChI=1S/C36H65N17O12S2.C2HF3O2/c1-17(54)27-33(63)52-19(7-4-10-44-35(40)41)29(59)47-14-26(57)49-23(34(64)65)16-67-66-15-18(38)28(58)46-13-25(56)48-22(12-24(39)55)32(62)51-20(6-2-3-9-37)30(60)50-21(31(61)53-27)8-5-11-45-36(42)43;3-2(4,5)1(6)7/h17-23,27,54H,2-16,37-38H2,1H3,(H2,39,55)(H,46,58)(H,47,59)(H,48,56)(H,49,57)(H,50,60)(H,51,62)(H,52,63)(H,53,61)(H,64,65)(H4,40,41,44)(H4,42,43,45);(H,6,7)/t17-,18+,19+,20+,21+,22+,23+,27+;/m1./s1
InChIKey SPBNDGIFBKBJLV-OHIMOQKDSA-N
SMILES C[C@H]([C@H]1C(=O)N[C@H](C(=O)NCC(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CCCN=C(N)N)CCCCN)CC(=O)N)N)C(=O)O)CCCN=C(N)N)O.C(=O)(C(F)(F)F)O
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