LXW7 TFA

For research use only. Not for therapeutic Use.

  • CAT Number: I045902
  • Molecular Formula: C31H49F3N12O14S2
  • Molecular Weight: 934.92
  • Purity: ≥95%
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LXW7 TFA(Cat No.:I045902)is a synthetic cyclic peptide supplied as a trifluoroacetate (TFA) salt, designed to selectively bind the integrin αvβ3 receptor. By targeting this receptor, which is highly expressed on endothelial cells and tumor vasculature, LXW7 promotes endothelial cell adhesion, survival, and angiogenesis. It has been studied for applications in tissue engineering, regenerative medicine, and targeted drug delivery. LXW7 TFA is particularly useful in biomaterial surface modification and vascularization studies, providing a research tool to investigate integrin-mediated signaling, angiogenesis, and therapeutic vascular remodeling.


Synonyms

2-[(4S,7R,10R,13S,19S,25S)-25-amino-4-carbamoyl-10-(carboxymethyl)-19-[3-(diaminomethylideneamino)propyl]-6,9,12,15,18,21,24-heptaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23-heptazacyclohexacos-13-yl]acetic acid;2,2,2-trifluoroacetic acid

Molecular Formula C31H49F3N12O14S2
Purity ≥95%
IUPAC Name 2-[(4R,7S,10S,13S,19S,25R)-25-amino-4-carbamoyl-10-(carboxymethyl)-19-[3-(diaminomethylideneamino)propyl]-6,9,12,15,18,21,24-heptaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17,20,23-heptazacyclohexacos-13-yl]acetic acid;2,2,2-trifluoroacetic acid
InChI InChI=1S/C29H48N12O12S2.C2HF3O2/c1-12(2)22-28(53)40-17(23(31)48)11-55-54-10-13(30)24(49)35-8-18(42)37-14(4-3-5-34-29(32)33)25(50)36-9-19(43)38-15(6-20(44)45)26(51)39-16(7-21(46)47)27(52)41-22;3-2(4,5)1(6)7/h12-17,22H,3-11,30H2,1-2H3,(H2,31,48)(H,35,49)(H,36,50)(H,37,42)(H,38,43)(H,39,51)(H,40,53)(H,41,52)(H,44,45)(H,46,47)(H4,32,33,34);(H,6,7)/t13-,14-,15-,16-,17-,22-;/m0./s1
InChIKey CABFZTZDDADZJM-YYLGFPHRSA-N
SMILES CC(C)[C@H]1C(=O)N[C@@H](CSSC[C@@H](C(=O)NCC(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N1)CC(=O)O)CC(=O)O)CCCN=C(N)N)N)C(=O)N.C(=O)(C(F)(F)F)O
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