Lutein

• CAT Number: R011774
• CAS Number: 127-40-2
• Molecular Formula: C40H56O2
• Molecular Weight: 568.87
• Purity: ≥95%
• Synonyms: (1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1R,4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol
• InChI: InChI=1S/C40H56O2/c1-29(17-13-19-31(3)21-23-37-33(5)25-35(41)27-39(37,7)8)15-11-12-16-30(2)18-14-20-32(4)22-24-38-34(6)26-36(42)28-40(38,9)10/h11-25,35-37,41-42H,26-28H2,1-10H3/b12-11+,17-13+,18-14+,23-21+,24-22+,29-15+,30-16+,31-19+,32-20+/t35-,36+,37-/m0/s1
• InChIKey: KBPHJBAIARWVSC-RGZFRNHPSA-N
• SMILES: CC1=C(C(CC(C1)O)(C)C)C=CC(=CC=CC(=CC=CC=C(C)C=CC=C(C)C=CC2C(=CC(CC2(C)C)O)C)C)C

Lutein (Cat No.: R011774) is a naturally occurring carotenoid found in high concentrations in green leafy vegetables, egg yolks, and corn. It plays a vital role in eye health by accumulating in the macula of the retina, where it acts as an antioxidant and filters harmful blue light. Lutein helps protect against age-related macular degeneration (AMD) and cataracts. It is also studied for its potential benefits in skin health and cognitive function. As a dietary supplement, lutein supports visual performance and overall ocular health.

Reference

[1]. Buscemi S, et al. The Effect of Lutein on Eye and Extra-Eye Health.Nutrients. 2018 Sep 18;10(9). pii: E1321.
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[2]. Kim SR, et al. Photooxidation of A2-PE, a photoreceptor outer segment fluorophore, and protection by lutein and zeaxanthin. Exp Eye Res. 2006 May;82(5):828-39.
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[3]. Tan D, et al. Lutein protects against severe traumatic brain injury through anti‑inflammation and antioxidative effects via ICAM‑1/Nrf‑2. Mol Med Rep. 2017 Oct;16(4):4235-4240.
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[4]. Zeni ALB, et al. Lutein prevents corticosterone-induced depressive-like behavior in mice with the involvement of antioxidant and neuroprotective activities. Pharmacol Biochem Behav. 2019 Apr;179:63-72.
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