LSN3318839

• CAT Number: I045215
• CAS Number: 2764704-18-7
• Molecular Formula: C26H23Cl2N3O2
• Molecular Weight: 480.39
• Purity: ≥95%
• Synonyms: (2R)-2-[2-[1-[(1R)-1-(2,6-dichloro-3-cyclopropylphenyl)ethyl]imidazo[4,5-c]pyridin-6-yl]phenyl]propanoic acid
• InChI: InChI=1S/C26H23Cl2N3O2/c1-14(26(32)33)17-5-3-4-6-19(17)21-11-23-22(12-29-21)30-13-31(23)15(2)24-20(27)10-9-18(25(24)28)16-7-8-16/h3-6,9-16H,7-8H2,1-2H3,(H,32,33)/t14-,15-/m1/s1
• InChIKey: JPJWHCNGSBCZMI-HUUCEWRRSA-N
• SMILES: C[C@H](C1=CC=CC=C1C2=NC=C3C(=C2)N(C=N3)[C@H](C)C4=C(C=CC(=C4Cl)C5CC5)Cl)C(=O)O

LSN3318839（Cat No.:I045215）is a potent, selective antagonist of the orexin 1 receptor (OX1R), a G protein–coupled receptor involved in regulating arousal, reward processing, and stress responses. By blocking OX1R signaling, LSN3318839 modulates neuronal activity in pathways linked to addiction, anxiety, and emotional regulation. It is a valuable research tool for studying orexin-mediated neurotransmission and its role in neuropsychiatric disorders. LSN3318839 holds therapeutic potential for treating substance use disorders, anxiety-related conditions, and other central nervous system diseases where dysregulated orexin signaling contributes to pathological behaviors and emotional dysregulation.