For research use only. Not for therapeutic Use.
LSN2463359（Cat No.:R014433）is a potent and selective inhibitor of vesicular monoamine transporter 2 (VMAT2), a protein responsible for packaging monoamines—such as dopamine, serotonin, and norepinephrine—into synaptic vesicles for release into the synaptic cleft. By inhibiting VMAT2, LSN2463359 reduces monoamine storage and release, making it useful for studying monoaminergic signaling, neurodegenerative diseases, and addiction. It is often used in preclinical models to investigate dopamine-related disorders, including Parkinson’s disease and schizophrenia. LSN2463359 serves as a valuable pharmacological tool for dissecting VMAT2 function and exploring therapeutic strategies targeting monoamine regulation.
| CAS Number | 1401031-52-4 |
| Synonyms | N-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide |
| Molecular Formula | C16H15N3O |
| Purity | ≥95% |
| IUPAC Name | N-propan-2-yl-5-(2-pyridin-4-ylethynyl)pyridine-2-carboxamide |
| InChI | InChI=1S/C16H15N3O/c1-12(2)19-16(20)15-6-5-14(11-18-15)4-3-13-7-9-17-10-8-13/h5-12H,1-2H3,(H,19,20) |
| InChIKey | STAFRSGTRKNXHF-UHFFFAOYSA-N |
| SMILES | CC(C)NC(=O)C1=NC=C(C=C1)C#CC2=CC=NC=C2 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
