For research use only. Not for therapeutic Use.
Loratadine-d₅（Cat No.:I045061）is a deuterated analog of loratadine, a long-acting, non-sedating antihistamine that selectively antagonizes peripheral histamine H₁ receptors. In this labeled form, five hydrogen atoms are replaced with deuterium, making it ideal as an internal standard in LC-MS/MS assays for the precise quantification of loratadine in biological samples. Loratadine-d₅ retains the pharmacological profile of the parent compound and is commonly used in pharmacokinetic, metabolic, and drug interaction studies.
| CAS Number | 1398065-63-8 |
| Synonyms | 1,1,2,2,2-pentadeuterioethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate |
| Molecular Formula | C22H18D5ClN2O2 |
| Purity | ≥95% |
| IUPAC Name | 1,1,2,2,2-pentadeuterioethyl 4-(13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-ylidene)piperidine-1-carboxylate |
| InChI | InChI=1S/C22H23ClN2O2/c1-2-27-22(26)25-12-9-15(10-13-25)20-19-8-7-18(23)14-17(19)6-5-16-4-3-11-24-21(16)20/h3-4,7-8,11,14H,2,5-6,9-10,12-13H2,1H3/i1D3,2D2 |
| InChIKey | JCCNYMKQOSZNPW-ZBJDZAJPSA-N |
| SMILES | [2H]C([2H])([2H])C([2H])([2H])OC(=O)N1CCC(=C2C3=C(CCC4=C2N=CC=C4)C=C(C=C3)Cl)CC1 |
| Chemistry Calculators | Dilution Calculator In vivo Formulation Calculator Molarity Calculator Molecular Weight Calculator Reconstitution Calculator |
